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   PULMONARY    NASAL
DirectHaler™ Nasal
Designed to solve key problems
Novel and improved nasal delivery
How can it appear so straightforward?
Proven performance and acceptability
Unique customisation options
Cost-effective manufacturability
Designed to solve key problems

The patented DirectHaler™ Nasal device and delivery method can solve or significantly reduce identified problems problems of currently marketed nasal delivery device systems.

A range of nasally delivered products has been on the market during recent decades. These products belong to therapeutic areas such as allergic rhinitis treatment, migraine relief, hormone replacement therapy (HRT) and common cold relief. 

The products have applied nasal delivery systems based primarily on four different formulation/device technology types: liquid nasal drops; liquid nasal sprays; pressurised metered-dose inhalers (HFA, CFC); and dry-powder inhalers and insufflators. Performance and characteristics of these nasal delivery systems have been studied widely, and various disadvantages have been identified.

The patented DirectHaler™ Nasal device and delivery method can solve or significantly reduce these problems.


Problems Solved by DirectHaler Nasal
Risk of liquid dose dripping out from nostril. Dry powder nasal dose sticks to nasal epitelium.
Risk of liquid dose swallowed immediately after delivery - giving limited absorption time and unpleasant taste. NasalSeal principle closes nasal cavity. Preventing immediate dose swallowing and taste disturbance.
Risk of "snorting-in" powder dose being inhaled to lungs. NasalSeal principle closes passage between oral and nasal cavity. Preventing inhalation to lungs.
Bulky insufflator devices limiting the portability and discretion in use. Compact device size ensures high portability and discretion in use.
Complicated and time-consuming insufflation device procedures making acute-use difficult. Easy-to-use and easy-to-instruct. Suitable for acute-use
Unpleasant "cold-blow" of medication from pMDI. Patient generated air-blow ensures convenient blow temperature perception in nasal cavity.
Unhygienic multi-use device concepts, necessitating preservatives in formulation and frequent device cleaning. DirectHaler™ Nasal is for single-use and is disposable. Does not require preservatives and cleaning.